capital bio human mrna microarray v2.0  (CapitalBio Corporation)

Journal: Frontiers in Genetics

Article Title: circARL15 Plays a Critical Role in Intervertebral Disc Degeneration by Modulating miR-431-5p/DISC1

doi: 10.3389/fgene.2021.669598

Figure Lengend Snippet: Heat map, volcano plots, GO annotation, and KEGG analysis of DEGs. (A–D) Heat map and volcano plots of circRNAs (A) , lncRNAs (B) , miRNAs (C) , and mRNAs (D) . The upper heat maps are based on expression values of significantly differentially expressed ncRNAs and mRNAs (absolute fold change ≥ 2.0 and p < 0.05) detected by microarray probes. “Red” and “Green” indicate expression above and below, respectively, relative expression. R = IDD group; N = control group. The bottom volcano plots reflect the number, significance, and reliability of differentially expressed ncRNAs and mRNAs. Red dots are up-regulated genes, green dots are down-regulated genes, and black dots are genes that were the same between the two groups. (E–H) GO annotation and KEGG analysis of differentially expressed mRNAs, with the top 15 enrichment scores covering domains of biological processes (E) , cellular components (F) , molecular functions (G) , and significant pathways (H) . Enrichment score values were calculated as –log 10 ( p -values). (I–K) The BP (I) , CC (J) , and MF (K) were visualized in Cytoscape.

Article Snippet: The GSE67567 dataset was acquired from the National Center of Biotechnology Information (NCBI) Gene Expression Omnibus database , on the basis of GPL15314 Arraystar Human LncRNA and mRNA microarray V2.0 (Agilent_033010 Probe Name version), GPL19449 Exiqon miRCURY LNA microRNA Array, 7th generation REV – hsa, mmu & rno (miRBase v18.0), and GPL19978 Agilent-069978 Arraystar Human CircRNA microarray V1.

Techniques: Expressing, Microarray

Journal: Frontiers in Oncology

Article Title: The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21

doi: 10.3389/fonc.2020.598238

Figure Lengend Snippet: DDX18 expressions in gastric cancer tissues. (A) DDX18 expressions from The Cancer Genome Atlas (TCGA). (B) DDX18 mRNA expression in 22 paired gastric cancer tissues. (C, D) DDX18 protein expressions in 10 paired gastric cancer tissues. (E) DDX18 expression by immunohistochemistry.

Article Snippet: The mRNA expression profile of the known protein in five cases of gastric cancer and adjacent tissues was analyzed by an Arraystar Human mRNA Microarray v2.0 gene chip.

Techniques: Expressing, Immunohistochemistry